Cheap Magazines | Bad Credit Mortgages | Payday Loan | Loan | Xbox Mod Chips
IQ Test - Why do autoimmune diseases run in families? [Archive] - FreeConservatives

PDA

View Full Version : IQ Test - Why do autoimmune diseases run in families?


StealthDeath
05-24-2006, 11:27 PM
Copyright Notice:
The following research is the property of StealthDeath. This information has been obtained utilizing standard search engines on documents available to public view on the Internet. However, you may not use this research beyond my postings here as I am claiming copyright to my library of information, which has taken 8 years to assemble. These abstracts, document sections and narration are provided here on FreeConservatives.com for criticism, news reporting, and education as a documentary presentation. Your participation is greatly appreciated and needed to help direct which information will be used to create a DVD presentation exposing fraudulent medical care in America.

Want to see something really scary?

I would like you to take a close look at my family medical history:


Father: Slipped disc lower back, Ankylosing Sponylitis, clogged arteries with multiple heart bypass surgeries, spontaneous collapsed lung, aortic aneurysm, lactose intolerance, explosive anger, bipolar, acid reflux, aphthous ulcers (oral), died of bone cancer.
Mother: Diabetes Type II then progressed to type I, out of control sugar requiring hospitalization, Gall Bladder disease, slipped disc lower back, arthritis, clogged arteries with multiple heart bypass surgeries, blood pressure problems, osteoporosis, dementia, peripheral neuropathy, kidney disease, diarrhea intestinal problems, blood in stools, lactose intolerance, acid reflux, macular degeneration, cataracts and glaucoma, chronic fatigue, muscle cramps, overweight, gingivitis.
Brother #1: Back pain, low blood sugar, lactose intolerance, acid reflux and explosive anger.
Brother #2: Gall Bladder problems, diarrhea intestinal problems, lactose intolerance, dyslexia, Attention Deficit Disorder and slow learner.
Sister: Cerebral Palsy, cataracts, eye coordination problems, arthritis in hips, explosive anger, kidney stones, lactose intolerance.
StealthDeath: Reiter’s Syndrome (reactive arthritis), juvenile arthritis, osteoporosis as a kid, peripheral neuropathy, fibromyalgia, classic Lupus rashes on face and torso, plaques in fingernails, muscle seizures in neck and legs, bad disc in back, folliculitis, chronic fatigue syndrome, acid reflux esophagitis, lactose intolerance, fused bones in tarsal bones of both feet, heart problems, vasculitis/rosacea, ADHD/Autism, rage (beyond anger), bipolar, inflammatory bowel disorder and diarrhea, chronic sore throats and illness as a child, low HDL, high LDL, overweight, uveitis/conjunctivitis, history of antibiotic associated colitis (Clostridium difficile), white blood count bouncing in and out of range, elevated red blood cell count, intermittent low-grade fevers 99.0 - 99.8F, blood in stools, contact petechia, tinnitus, aphthous ulcers (oral), gingivitis, sleep deprivation.
StealthDeath’s Wife: Antiphospholipid Antibody Syndrome (APLA) Anticardiolipid Antibodies, raised blood sedimentation rate, anemia, inflammatory cells on PAP smear, infertility after first child, occasional stomach digestive problems, chronic fatigue, lactose intolerance, occasional muscle cramps.
StealthDeath’s Daughter: lactose intolerance, weak muscles despite karate lessons, intestinal discomfort, has had bouts of dizziness, has had some long-term respiratory illnesses (takes her longer to get over colds than other children her same age)


Now I would like you to look at some excerpts from an article. Notice my wife has APLA and I have C. difficile:



Contact: Stephanie Tonnesen
Carway Communications, Inc. 212-378-2020
For more information please call AARDA at (586) 776-3900.
AARDA PRESS RELEASE 11/95 - Study in American Journal of Medicine, Nov. 1995 Issue.
Link: http://www.aarda.org/press_release_display.php?ID=12 (http://www.aarda.org/press_release_display.php?ID=12)



Antibody Associated with Autoimmune Disorders Found to "Cluster" in Families



Finding May be First Step in Preventing Premature Stroke, Heart Attack and Miscarriage



<HR>
Detroit, November, 1995 An antibody traditionally associated with rheumatic autoimmune diseases such as lupus, has been identified as a "common thread" in families where at least one member suffers from an autoimmune disorder associated with high levels of the antibody.

The research, conducted by investigators at Yale University School of Medicine and St. Mary's Hospital in Waterbury, Connecticut, was published in the November issue of the American Journal of Medicine.

The antibody, known as the antiphospholipid antibody (APL), is one of a class of antibodies referred to as auto-antibodies. Common to autoimmune diseases, auto-antibodies are proteins produced by the body to attack itself, rather than invading viruses and bacteria. APL is made to fight certain good body fats called lipids. When the level of APL is high and these proteins float freely throughout the blood, a disease state occurs. The antiphospholipid antibody syndrome (APS) is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis (clot in the vein) and pulmonary thromboembolism (blockage of an artery found in the lung due to a clot that has traveled from a vein). It is also associated with low platelet or blood elements that prevent bleeding.

Recently, however, even more disease states have been linked with APL including premature heart attack, migraine headaches, various cardiac valvular abnormalities, skin lesions, diseases that mimic multiple sclerosis, vascular diseases of the eye that can lead to visual loss and blindness, and early peripheral vascular disease that can result in amputations of the extremities and digits.

The St. Mary's/Yale study looked at 23 individual family members with APS, 87 of their blood relatives, 18 spouses and 37 controls. Overwhelmingly, it found clustering of the APL antibody in families. Of the 87 blood relatives, some 50 — or nearly 60% — had auto-antibodies, compared with only one spouse. Approximately 33 percent or one-third had antiphospholipid antibodies, while another 37 percent had other auto-antibodies, such as anti-nuclear antibodies. None of the controls tested positive.


The study also found that more relatives had suffered from one of the manifestations of APS than did either the spouses or controls. Indeed, several relatives were found to have either lupus (4) or lupus-like syndrome (4), premature stroke (2), recurrent fetal loss (3), recurrent thrombosis (1) or thrombocytopenia (2). "


…"the APL antibody may be associated with one disease process in one family member and yet another disease process in another family member," said Thomas Greco, M.D., assistant clinical professor of medicine, Yale University School of Medicine, and chief, Section of Inflammatory Diseases, St. Mary's Hospital.

Recent data presented by French researchers at the October meeting of the American College of Rheumatology also support the findings of Drs. Greco, Goldberg and Kelly. In a study on families with antiphospholipid antibodies, many relatives were found to have diseases related to these proteins as well as many other immunologic diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome, Crohn's disease, multiple sclerosis, low platelets (ITP), thyroid disease and others.


Observe the following…

IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum

Castagliuolo, C. P. Kelly, B. S. Qiu, S. T. Nikulasson, J. T. LaMont and C. Pothoulakis

Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02215, USA.

Interleukin-11 (IL-11) is a stromal cell-derived cytokine with several<SUP> </SUP>biological activities against hematopoietic cells. Recent results indicated<SUP> </SUP>that IL-11 reduced mucosal damage in animal models of colitis. This study<SUP> </SUP>aimed to explore the action of recombinant human IL-11 (rhIL-11) on the<SUP> </SUP>intestinal effects of Clostridium difficile toxin A, an inflammatory<SUP> </SUP>enterotoxin, and cholera toxin, a noninflammatory enterotoxin in rat ileum.


Link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9277411&dopt=Abstract


I would like you to look at this abstract of a patent filed by a company that employs MIT biologists.

U.S. Class 424/78.04
Patent Number 5948402
Issue Date 1999 09 07
Assignee Genetics Institute, Inc. Inventor(s) Keith, James Schendel, Paul Title

Method of using IL-11 for treating antibiotic induced diarrhea

Abstract Provided by the present invention are methods of treating a variety of disorders including AIDS, arthritis (rheumatoid arthritis, osteoarthritis, spondyloarthropathies), antibiotic induced diarrheal diseases (Clostridium difficile), multiple sclerosis, osteoporosis, gingivitis, peptic ulcer disease, esophagitis, diabetes, retinitis, uveitis, reperfusion injury after myocardial infarction (MI) or cerebral vascular accident (CVA), aphthous ulcers (oral), atherosclerosis (plaque rupture), prevention of tumor metastases, asthma, preeclampsia, and allergic disorders such as rhinitis, conjunctivitis, and urticaria.


Exmp. Claim 1
Ex Claim text A method of treating an antibiotic induced diarrheal disease, comprising administering a pharmaceutically effective amount of IL-11


Link: http://xrint.com/patents/us/6126933


They filed more than one patent…

Title: Method of using IL-11 for treating gingivitis

United States Patent: 6,270,759
Inventors: Keith; James (Andover, MA); Schendel; Paul (Wayland, MA)
Assignee: Genetics Institute, Inc. (Cambridge, MA)
Appl. No.: 337965
Filed: June 22, 1999



Abstract


Provided by the present invention are methods of treating a variety of disorders including AIDS, arthritis (rheumatoid arthritis, osteoarthritis, spondyloarthropathies), antibiotic induced diarrheal diseases (Clostridium difficile), multiple sclerosis, osteoporosis, gingivitis, peptic ulcer disease, esophagitis, diabetes, retinitis, uveitis, reperfusion injury after myocardial infarction (MI) or cerebral vascular accident (CVA), aphthous ulcers (oral), atherosclerosis (plaque rupture), prevention of tumor metastases, asthma, preeclampsia, and allergic disorders such as rhinitis, conjunctivitis, and urticaria

Link: http://www.pharmcast.com/Patents/Yr2001/August2001/080701/6270759_IL11080701.htm

And another…

Method of using IL-11 for treating mucositis
Document: United States Patent 6887461

Abstract: Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis).

Link: http://www.freepatentsonline.com/6887461.html


Another company altogether…


Title: Method of treating inflammatory bowel disease using a topical formulation of IL-11
United States Patent: 6,540,993
Issued: April 1, 2003
Inventors: Warne; Nicholas W. (Andover, MA); Bedrosian; Camille L. (Belmont Hills, MA); Keith, Jr.; James C. (Andover, MA); Schwerschlag; Ullrich S. (Beverly Farms, MA); Schendel; Paul F. (Wayland, MA)
Assignee: Wyeth (Madison, NJ)
Appl. No.: 662994
Filed: September 15, 2000




Abstract


Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis
Link: http://www.pharmcast.com/Patents/Yr2003/April2003/040103/6540993_Inflammatory040103.htm (http://www.pharmcast.com/Patents/Yr2003/April2003/040103/6540993_Inflammatory040103.htm)


Who on this forum is smart enough to realize what you have just seen?

If you don’t get it keep reading my posts. Your life depends on it.